Pan Lab
Membrane Biophysics
Research interests
- Peptidomimetics (peptide mimics) interacting with bacterial membranes
- Protein aggregates (e.g., oligomers and fibrils) interacting with lipid membranes
- Phase separation in model lipid bilayers
- Amphipathic peptides modulate lipid membrane curvature and structure
| Experimental Images | Description |
|---|---|
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Phase separation of lipid bilayers revealed by atomic force microscopy. |
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Giant unilamellar vesicles (GUVs) acting as a platform for observing phase separation. The two images below were obtained using fluorescence microscopy. |
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Micropipette aspiration of giant unilamellar vesicles. This technique is useful to reveal kinetic impacts of active molecules on vesicle morphology and integrity. |
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AFM images of different forms of amyloid aggregates. |
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Imaging bacterial morphology using atomic force microscopy. |
Research Support
Title: Characterizing Interactions between Bacterial Membranes and Peptidomimetics for the Development of Antibiotics Targeting Multidrug Resistant Bacteria.