Research

Past Studies

Research is the backbone of science. By being a research participant, you have the ability to contribute to science while also learning about yourself. We could not conduct research without our participants and are thankful to every one of them.

Project: A randomized, double-blind, placebo-controlled phase ½ study of OTO-413 given as a single intratympanic injection in subjects with speech-in-noise hearing impairment

Eligibility:Patients must be 21-64 years old with complaints of trouble hearing in background noise.
Goal: To evaluate an investigational drug that is delivered directly in the ear through the eardrum.                                                                                                                                                 

Project: A Phase 2a, Prospective, Randomized, DoubleBlind, Placebo Controlled, Single and Repeat-Dose, Multicenter, Exploratory Efficacy Study of FX-322 Administered by Intratympanic Injection in Adults with Stable Sensorineural Hearing Loss

Eligibility: Participants must be between 18-65 years old with an established diagnosis of stable sensorineural hearing loss by standard hearing tests.                                 
Goal: To evaluate a new investigational medication called FX-322 that is delivered directly in the ear through the eardrum.                                                                                                                

Project: Aging and Cognition Health Evaluation in Elders (ACHIEVE RCT)

Eligibility: Adults ages 70-84 with sensorineural hearing loss.
Goal: To determine the feasibility of delivering a best practices hearing rehabilitative intervention protocol with older adults with hearing loss.

Project: Application of Health Behavior Models to Predict Hearing Healthcare Outcomes

Eligibility: Adults greater than 50 years old who fail a hearing screening in the community.
Goal: To better understand the relationship between an adult's hearing health care behaviors and his/her attitudes and beliefs about hearing healthcare and readiness for behavior change.

Project: Word Recognition in Quiet Performance: Effects of the Carrier Phrase

End date: April 2018
Overview: The purpose of this study is to compare word recognition performance in quiet with and without the inclusion of a string of words presented to the listener immediately before the presentation of the target word, known as a carrier phrase, among young healthy adults with normal hearing and older healthy adults with hearing impairment. This research study is designed to assess test validation and reliability among standardized word recognition materials. Participation in this study requires two, two hour visits to the lab. During the visit participants will complete hearing and speech testing in a sound booth in quiet.

 

Project: Cochlear Implant Speech Perception

End date: Spring 2018
Overview: The purpose of this study is two-fold. The first goal in this study is to determine if a specific speech in noise program yields a better speech perception score for cochlear implant users. A second goal is to determine if the test required for this study could help facilitate a new clinical protocol for determining which input processing should be used for specific cochlear implant users at the University of South Florida. Participation in this study requires one, two-hour visit to the lab. During the visit participants will complete speech testing in a sound booth in quiet and in noise.

 

Project: Evaluation of a Spanish Hearing Loss Toolkit for Self-Management

End date: Spring 2018
Overview: The purpose of this study is two-fold. The first goal in this study is to determine if the Spanish Hearing Loss Toolkit for Self-Management that was developed it appropriate and helpful for Spanish-speaking patients. A second goal is to determine what changes, if any, would need to be made in order to improve the toolkit for future clinical use for Spanish-speaking patients. Participation in this study requires two, one-hour visit to the lab. During the first visit participants will complete a feedback form on each section in the toolkit and participate in a short interview to discuss the toolkit. During the second visit participants will meet as a group and discuss the toolkit.

 

Project: Evaluation of a hearing Loss Toolkit for Self-Management

End date: February 2017
Overview: The study aims to evaluate materials created for the self-management of hearing loss. The materials were created based on feedback from the ARCT Lab's previous study, ACHIEVE-F.

Project: Hearing, Cognition, and Hearing Evaluation in Elders-Feasibility

Eligibility: Adults ages 70-84 with sensorineural hearing loss Goal: To determine the feasibility of delivering a best practices hearing rehabilitative intervention protocol with older adults with hearing loss.

Principle Investigator: Theresa Chisolm, Ph.D., CCC-A

IRB Protocol Number: USF Pro00020767

ACHIEVE-F: The purpose of this study is to determine the feasibility of delivering a best practices hearing rehabilitative intervention protocol with older adults with hearing loss. Each participant is in the study for six months and visits the lab 7 times during this time period. Participants are fit with state-of-the-art hearing aids at the beginning of the study and are expected to wear these hearing aids for the duration of the study. Participants will also receive auditory rehabilitation throughout the study. Outcomes are measured through various hearing and lifestyle questionnaires. Once a participant completes the study, he is allowed to keep the hearing aids and assistive listening devices provided to him during the study.

Project: A Balanced, Randomized, Placebo-Controlled, Double-Blind Study of the Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss

End date: June 2016
Overview: This study aims to evaluate the efficacy of the drug AUT00063 (CLARITY-1) on the ability to understand speech in noisy environments

Project: Epidemiology of Diabetes Interventions and Complications (EDIC)

End Date: March 2016
Overview: The primary mission of the EDIC study is to determine the effects of glycemic control and of non-hyperglycemic risk factors on the complications of type 1 diabetes. We are one of multiple sites in the nation collecting data for EDIC.

Project: Audiologic Profile of Individuals with Friedreich's Ataxia

End date: September 2015
Overview: Within collaboration with USF Department of Neurology, this study aims to investigate the auditory behavioral and electro-physiological profile of individuals with Friedreich's Ataxia as part of a larger clinical drug trial (Safety and Efficacy of EPI-743, clinicaltrials.gov identification: NCT0128064).

 

These studies are no longer accepting new participants. If you are interested in participating in other research studies in our lab or would like to be contacted for new studies, please call us at 813-974-1262.